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1.
Journal of Sheikh Zayed Medical College [JSZMC]. 2017; 8 (1): 1105-1107
in English | IMEMR | ID: emr-187074

ABSTRACT

Background: Pilonidal sinus disease is a common condition often seen in young adults, affecting male twice then the female. Many surgical and non- surgical treatment modalities have been suggested


Objective: To evaluate the results of rhomboid excision and Limberg flap reconstruction in the treatment of pilonidal sinus disease


Methodology: This cross-sectional study was carried out at Surgical Department Unit-II Sheikh Zayed Medical College and Hospital, Rahim Yar khan. The study was conducted from 1 June 2014 to 31 January 2016. A total of 34 patients were included in this study. Patients having primary pilonidal sinus disease underwent this operation. Data analysis was carried out by using SPSS Version16 software


Results: 34 patients has undergone this surgery. All study subjects were males. The mean age was 26 years [Range: 18-36 years]. No patient presented with recurrent pilonidal sinus. The mean operative time was 55 minutes and ranged from 45 to 65 minutes. Hospital stay ranged from 3 to 4 days. Two [5.88%] patients has minimal epidermolysis of flap corners. Two [5.88%] has slight gaping of wound edges. However all four healed completely with conservative treatment. One patient has persistent discharge which took 3 weeks to settle down. 100% success rates with no recurrence was achieved


Conclusion: Limberg flap technique is very effective for pilonidal sinus disease with low complication and excellent success rates

2.
Anaesthesia, Pain and Intensive Care. 2017; 21 (1): 19-24
in English | IMEMR | ID: emr-187458

ABSTRACT

Introduction: Postoperative nausea and vomiting [PONV] occurs in patients during the first 24 hours of the surgery. Many drugs have been used for the prevention and treatment of PONV. In this trial, we used gabapentin to evaluate its prophylactic effect in reducing the severity and incidence of PONV in patients undergoing diagnostic laparoscopic gynecological surgery


Methodology: This, double blind randomized controlled trial, was done in operation theatre complex over a period of six months. 140 patients undergoing diagnostic gynecological laparoscopic surgery were selected. Two groups were formed and 70 patients were recruited in each group using lottery method as method of randomization. Group C [control group] was given placebo medication orally two hours before surgery and group G [gabapentin group] received 600 mg of gabapentin orally two hours before the procedure. Standard general anesthesia technique was used in all patients and incidence and severity of postoperative nausea and vomiting [PONV] was recorded in these patients till 24 hours of laparoscopy


Results: Severity of PONV was graded from mild to severe. There was no PONV in 25 patients [35.7%] in group C and 47 patients [67.1%] in group G. It was mild in severity in 8 patients [11.4%] in group C and 5 patients [7.1%] in group G, moderate in 31 patients [44.3%] in group C and 15 patients[21.4%] in group G and severe PONV was seen in 6 patients [8.6%] in group C and 3 patients [4.3%] in group G [P=0.003]. Postoperative nausea and vomiting within 24 hours after procedure was present in 45 patients [64.3%] in group C and 23 patients [32.9%] in group G. Results were significant between two groups after statistical analysis with p value of 0.001


Conclusion: Administration of 600 mg of gabapentin two hours before diagnostic gynecological laparoscopy decreases the frequency and severity of PONV


Subject(s)
Adult , Humans , Female , Young Adult , Amines/therapeutic use , Cyclohexanecarboxylic Acids/therapeutic use , gamma-Aminobutyric Acid/therapeutic use , Laparoscopy , Double-Blind Method
3.
Medical Forum Monthly. 2013; 24 (9): 53-56
in English | IMEMR | ID: emr-161161

ABSTRACT

Early assessment of outcome by ST segment elevation after acute myocardial infarction. Observational study. This study was conducted at Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot from 1[st] January 2012 to 30[th] April 2013. 160 cases of acute myocardial infarction were randomly selected from the patients attending to OPD and emergency of Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot and their peripheral Districts. During the study period, 160 patients met the criteria for inclusion and were given thrombolytic therapy. Out of these, 136 [85%] patients were males and 24 [15%] patients were females. Mean age at the time of presentation was 51.0 tears. 91 [56.8] patients had acute anterior myocardial infarction, 58 [36.2%] had acute inferior myocardial infarction and 11 [6.8%] patients had miscellaneous findings. Average time lapse was 4.03 hours from onset of the chest pain to administration of streptokinase. Group A' [complete ST segment resolution] included 67 [41.8%] patients while there were 49 [30.6%] patients in group 'B' [partial ST segment resolution] and 44 [27.5%] patients on group 'C' [no ST segment resolution]. The ST segment was raised in all of the acute myocardial infarction cases. But ST segment was resolved in patients in which streptokinase injection was given 4 to 5 hours back

4.
Medical Forum Monthly. 2013; 24 (11): 10-12
in English | IMEMR | ID: emr-161172

ABSTRACT

To study the incidence of appendicitis with relation to age, sex, occupation, socio economic status, dietary habits and urban or rural area of district Sialkot. Retrospective study. This study was conducted at the Islam Teaching Hospital Sialkot from 1[st] January 2012 to 31 December 2012. 100 cases of appendicitis were randomly selected from the patients attending to OPD and emergency of Islam Teaching Hospital Sialkot and its peripheral Districts. The data was collected on written pro forma and analyzed for results. In this study the incidence of appendicitis was the highest 39 % at the age 11 - 20 years and the lowest at the age of 71 - 80 years [03 %] It was seen that incidence of appendicitis was 52 % [52 cases] in male and 48 % [48 cases] in female as shown in Table No.2. The incidence was the highest in students 36 % [36 cases] as compared to business man 03 % [03 cases] as shown in Table No.3. In this study the incidence of appendicitis was 37 % [37 cases] in people having high fiber diet as compared to those people who had low fiber diet 63 % [63 cases] as shown in Table No 4. The incidence of appendicitis was 62 % [62 cases] in people living in urban area has compared to people living in rural area 38 % [38 cases] which was half of the urban area as shown in Table No 5. At the last it was seen that the incidence was 60 % [60 cases] in lower class and 40 % [40 cases] high gentry as shown in Table No 6. The incidence of appendicitis is much more in 11-20 year of age and Males were more prone as compare to Female. Students and laborers were more prone as compared to other groups of patients. Low fiber dietary habits were more in percentage as compared to patient having high fibre dietary habits and percentage of patients of appendicitis were double in Urban area as compared to rural area. The incidence of appendicitis was more in patients of low socio economic status as compared to high socio economic status

5.
Medical Forum Monthly. 2013; 24 (10): 16-19
in English | IMEMR | ID: emr-161198

ABSTRACT

To study the incidence of Bacteria resistance to antibiotics in hospitals. Experimental study. This study was conducted at Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot from 1[st] January 2012 to 30[th] April 2013. 100 cases of Bacteria resistance to antibiotics in hospital patients were selected by doing culture and sensivity test in labs of Shaheena Jamil hospital Abbottabad and Islam teaching hospital Sialkot. Bacteria resistant to Penciline was the most highest, 147 cases [36.75%] and the lowest incidence of bacteria resistant to Levofloxin, 20 cases [05%] as shown in table No.l. The incidence of bacteria resistant to antibiotics with relation to age was maximum at 1-10 years, 15 cases [3.75%] and maximum in age group 21-30 years, 105 cases [25.75%] as shown in table No.2. The incidence of bacteria resistant to antibiotics in females were, 207 cases [51.75%] and in male, 193 cases [48.25%] as shown in table No.3. The incidence of bacteria resistant to antibiotics was the highest in office servants and factory workers, 54 cases [13.50%] and 53 cases [13.25%] respectively and the lowest in students, 20 cases [05%] as shown in table No.4. The incidence of bacteria resistant to antibiotics was highest in middle class of peoples, 189 cases [47.25%], 159 cases [39.75%] in low socio-economic group of peoples and 52 cases in high gentry, 52 cases [13%] as shown in table No.5. The incidence of bacteria resistant to antibiotics was more in peoples living in rural area, 221 cases [55.25%] as compared to peoples living in urban area. 179 cases [44.75%] as shown in table No.6. The incidence of Bacteria resistance to antibiotics was rising day by day misuse of antibiotics, therefore the use of antibiotics should be only by a qualified doctor prescription

6.
Medical Forum Monthly. 2013; 24 (8): 27-30
in English | IMEMR | ID: emr-147928

ABSTRACT

To study the incidence of Inguinal Hernia with relation to age, sex, occupation, socio economic status, dietary habits and urban or Rural area of District Sialkot and its peripheral districts. Original study. This study was conducted at Islam Teaching Hospital Sialkot from 1[st] January 2012 to 31[st] December 2012. 100 cases of Inguinal Hernia were selected randomly from patients attending to OPD and emergency of Islam Teaching Hospital Sialkot. The result are shown in the Table No. 1 to Table No. 6. There was maximum percentage of Inguinal Hernia in age group 10-20 years [24%] and minimum in age group 81-90 years [04%] [Table No. 1]. The incidence of Inguinal Hernia was maximum in male [80%] as compared to female [20%] as shown in Table No. 2. There was maximum incidence of Inguinal Hernia in students [28%] and in factory workers, laborers, farmers was [20%] in each group and minimum in shop keepers and service men [06%] in each group as shown in Table No. 3. The incidence of Inguinal Hernia was maximum in people of low socio economic status [50%], [35%] in middle class and [15%] in people of high class as shown in Table No. 5. The incidence of Inguinal Hernia was [66%] in patients on low fibre diet and [34%] in patients on normal fibre diet as shown in Table No. 4. The incidence of Inguinal Hernia was [70%] in patients coming from rural area and [30%] in patients coming from Urban area as shown in Table No. 6

7.
Medical Forum Monthly. 2013; 24 (8): 43-46
in English | IMEMR | ID: emr-147932

ABSTRACT

To study the incidence of Hepatitis A, B and C with relation to age, sex, occupation, socio economic status, medical and surgical treatment, blade used for shaving and urban or rural area of Hazara division and district Sialkot. Original study. This study was conducted at Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot from 1[st] January 2010 to 30[th] April 2013. 300 cases of Hepatitis A, B and C were randomly selected from the patients attending to OPD and emergency of Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot and their peripheral districts. Results are shown in Table No. 1 to Table No. 9. The sanitary conditions of drinking water should be improve. The medical and paramedical staff should take care against syringe needle prick, surgical knife cut and blood transfusion. In barber shop during hair cutting and clean shave the blade should be new one and not reused. The sexual contact should be restricted to the life partner. The dental surgery is also one toll for Hepatitis spread. The aggravating factors such as occupation and socio economic status, medical and surgical treatment, blade used for shaving, surgical instruments, syringe, blood transfusion dentistry instruments should be free of infection and sanitary conditions should be improved

8.
Medical Forum Monthly. 2013; 24 (8): 55-58
in English | IMEMR | ID: emr-147935

ABSTRACT

To study the incidence of tuberculosis in patients with relation to age, sex, occupation, socio economic status, medical and surgical treatment, blade used for shaving and urban or rural area of Hazara division and district Sialkot. Original study. This study was conducted at Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot from 1[st] January 2010 to 30[th] April 2013. 500 cases of tuberculosis were randomly selected from the patients attending to OPD and emergency of Shaheena Jamil Teaching Hospital Abbotabad and Islam Teaching Hospital Sialkot and their peripheral districts. Results are shown in Table No. 1 to Table No. 5. The maximum incidence of tuberculoses was in age group [31-40 years] and 23.4%. The incidence of tuberculoses was in age group 71-80 years [08%] which was minimum with relation to age group as shown in Table No. 1. There was more incidence of tuberculosis [55.4%] in women as compared to men [44.6%] because men have more resistance against tuberculosis as compared to women as shown in Table No. 2. As shown in Table No. 3 the victims of tuberculosis were maximum in laborer [23%] and factory workers [22.2%] and minimum incidence of tuberculosis was found [1.6%] in house wives as compared to other groups of people. There was maximum incidence of tuberculosis in low socio economic group of people [65.4%] in middle class of people and 2.8% in high gentry as shown in Table No. 4. Which was minimum as compared to other groups of people. As shown in Table No. 5 there was 42.6% incidence of tuberculosis as compared to rural area 57.4%

9.
Zanco Journal of Medical Sciences. 2013; 17 (1): 337-343
in English | IMEMR | ID: emr-142736

ABSTRACT

Fatigue, is a common presenting symptom in primary care which negatively impacts work performance, family life, and social relationships. The aim of this study is to determine the causes of fatigue and to explore the relationship between fatigue and physical, mental, social and demographic factors among patients with special reference to gender. A cross sectional study was carried out at the Brayati Family Medicine Center in Erbil city from 1st of July to the 31st of October 2011. We studied 320 patients of both genders attending the center for various reason complaining from fatigue. Formal consent was obtained. Demographic data in addition to two questionnaires were completed, Lowa fatigue scale and Hospital Anxiety and Depression Scale. 86 males [26.88%] and 234 females [73.12%]. The age of the subjects varied from 16-74 years .The mean age was 29.2 years, 39.69% were in the age range 30-44 years. 58.12% were illiterate or read and write only; 65.63% were married and 57.19% re-ported their economic level as medium. 38.44% were fatigued according to lowa fatigue scale. Higher level was detected among older age group, singles, and low economic and minimum educational status [51.16%, 45.31%, 41.80%, 41.18 and 42.57% respectively]. Depression was significantly associated with fatigue, 70% of patients who were depressed complained from fatigue. Findings indicated that, in addition to increasing anxiety among the study sample, higher levels of fatigue were detected in 61.36% of them. Fatigue as a symptom is very common both in community and health care settings but remains medically unexplained. The most important confounders in our studied population were depression and anxiety


Subject(s)
Humans , Male , Female , Depression/complications , Anxiety/complications , Primary Health Care , Delivery of Health Care , Surveys and Questionnaires , Community Health Services , Cross-Sectional Studies , Educational Status
10.
Journal of Sheikh Zayed Medical College [JSZMC]. 2012; 3 (2): 301-304
in English | IMEMR | ID: emr-195699

ABSTRACT

Background: De Quervian's disease, which is painful inflammation of first dorsal compartment of wrist, and surgical, non surgical treatment modalities are being used for its management


Objective: To compare the frequency of pain among patients of de Quervian's disease managed by surgical decompression and steroid injection methods


Patients and Methods: This was an experimental study, conducted at Orthopedic Complex in Bahawal Victoria Hospital, Bahawalpur for six months from October 2009 to March 2010.We inducted 66 patients fulfilling the inclusion criteria. The patients were randomly divided into two groups. Group A patients were managed by surgical decompression and group B patients by steroid injection. After 4 weeks pain relief was assessed on the basis of Finkelstein's test result and visual analogue scale was used to describe the level of pain by patients


Results: The mean age of the patients in group A was 42 +/- 9 years and in group B was 42.2 +/- 10.7 years. The Male to female ratio was 1:6 in both groups. In distribution of pain relief, in group A there were 26[78.7%] patients who got complete relief of pain, 4[12.1%] patients who had mild pian, 2[6%] patients who had moderate pain and 1 [3%] patients who had severe pain. While in group B there were 22 [66.6%] patients who got complete relief of pain, 6 [18%] patients who had mild pain, 3 [9%] patients who had moderate pain and 2[6%] patients who had severe pain


Conclusion: Our study suggests that surgical decompression is a better treatment option than steroid injection because it has more chances of complete pain relief and permanent cure from the disease

11.
Medical Forum Monthly. 2011; 22 (2): 39-43
in English | IMEMR | ID: emr-146380

ABSTRACT

The present work was designed to study the incorporation of newly synthesized myosin alkali light chain [MLC] molecules into myofibris. cDNA of fast skeletal muscle type of MLC tagged with green fluorescence protein [LC3f-GFP] was transfected into cultured chicken cardiomyocytes, and the assembly of expressed LC3f-GFP was observed in living cells under a fluorescence microscope equipped with a cooled CCD camera. At 14-16 hours after transfection, LC3f-GFP was diffusely distributed in the cytoplasm of cardiomyocytes. In some cells, however, intense fluorescence spots of LC3f-GFP were found along myofibrils with a periodically of 1.2 micro m. Confocal microscopy of such cells, stained with rhodamine-labeled phalloidin, revealed the fluorescence spots of LC3f-GFP localized at both ends of A-bond. When these cells were further incubated, LC3f-GFP came to be localized at all levels of the A-bands by 26 hours after transfection. These results indicate that myosin filaments are not replaced with newly synthesized myosin molecules at once along their length, but molecules in filaments are replaced individually from their ends


Subject(s)
Animals , Myofibrils , Transfection , Microscopy, Fluorescence , Chickens , Microscopy, Confocal , Cell Culture Techniques
12.
Professional Medical Journal-Quarterly [The]. 2011; 18 (1): 139-141
in English | IMEMR | ID: emr-109854

ABSTRACT

Despite advances in the prevention and treatment of hypertension over the past decade, hypertension remains an important public health challenge. Recent efforts to reduce the prevalence of hypertension have been focused on non-pharmacologic means, specifically diet. An increased intake of magnesium has been shown in some but not all studies to reduce blood pressure in patients with hypertension. Decreased Serum magnesium levels are associated with development of hypertension. This study was planned to investigate relation of serum magnesium with blood pressure in patients with mild uncomplicated hypertension. Study was conducted at LUMHS hospital Jamshoro and DHQ hospital charsadda for the period of six months. Fifty known cases of uncomplicated mild hypertensive patients were selected, same number of healthy controls were also examined. When results were summed up and test parameters were compared, it was seen that no significant differences were found in serum magnesium levels among both groups, when compared statistically. Finally we conclude that no relation of magnesium with hypertension was observed. Much more work on wide scale population may be needed to clarify the idea


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Magnesium/blood
13.
Professional Medical Journal-Quarterly [The]. 2011; 18 (2): 243-244
in English | IMEMR | ID: emr-124008

ABSTRACT

Geographical variation in the rates of kidney stones has been observed for many years. Pakistan is situated in stone belt. Calculus diseases is endemic in Pakistan, perhaps the incidence in Pakistan is highest in the world. To evaluate etiology and biochemical risk factors [inorganic phosphate] in the Peshawar. Study was conducted at LHR and Hayatabad Hospitals of Peshawar for the period of nine months. Two hundred patients and same number of controls were selected. The mean value of mean inorganic phosphate in non stone formers were less than that of stone formers. The mean of urinary inorganic phosphate excretion in stone formers was greater than that of non-stone formers. We conclude that inorganic phosphate is an independent risk factor for renal stone formation


Subject(s)
Humans , Female , Male , Calcium/blood , Calcium/urine , Risk Factors , Phosphates/blood , Kidney Calculi/epidemiology , Phosphates/urine
14.
Journal of Sheikh Zayed Medical College [JSZMC]. 2011; 2 (4): 236-238
in English | IMEMR | ID: emr-194780

ABSTRACT

Background: Hypoglossal Nerve [HGN] is known to be a pure motor [General somatic efferent] cranial nerve


Objective: To confirm the existence, localization and morphology of the neurons contributing sympathetic fibers to the Hypoglossal nerve [HGN]. Material and Methods: This experimental animal study, was conducted in Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi, from 1992 to 1995. Under general anesthesia the required hypoglossal nerves of twenty four albino rats were exposed and cut in the neck. Horseradish Peroxidase [HRP] crystals were applied to the central cut ends of the nerves and allowed to travel for about 48 hours. After transcardial fixation with 1.25% gluteraldehyde and 1% paraformaldehyde solution, serial sections of superior, middle and inferior cervical ganglia of both sides were made on a freezing microtome, treated with Tetramethylbenzidine [TMB] and counterstained by 1% neutral red. Labeled neurons were observed with the help of light microscope


Results: In all animals, the HRP labeled neurons contributing sympathetic fibers to the right and left hypoglossal nerves and their branches were located in the ipsilateral superior cervical ganglia only. Neurons were oval and rounded in shape, and randomly distributed in the ganglia. Average soma diameter of the neurons ranged between 6 to 38 microns


Conclusion: Hypoglossal nerve also contains sympathetic fibers which are contributed by ipsilateral superior cervical ganglion cells

15.
Professional Medical Journal-Quarterly [The]. 2010; 17 (4): 698-701
in English | IMEMR | ID: emr-118023

ABSTRACT

To evaluate the effects of serum calcium and urinary calcium excretion on upper urinary tract stone diseases in the Peshawar [a high stone incidence belt]. One hundred patients [age 20-60 years] who were suffering severely from upper urinary tract stone disease were selected from LRH and Hayatabad Medical Complex Hospitals of Peshawar, same numbers of healthy controls from the same region were also selected for the study. When results were summed up and test Parameters were compared, it was seen that mean serum calcium in stone formers was greater than that of non-stone formers [P<0.001]. Same pattern was also observed [P< 0.001] in both groups regarding mean urinary calcium excretion. We concluded that calcium is a definitive risk factor in upper urinary tract stone disease. However we suggest further work and research on wide scale population in order to evaluate this relation


Subject(s)
Humans , Female , Calcium/urine , Urinary Calculi/etiology , Urolithiasis/etiology , Risk Factors , Evaluation Studies as Topic
16.
Zanco Journal of Medical Sciences. 2010; 14 (1): 16-21
in English | IMEMR | ID: emr-129163

ABSTRACT

Quality of antenatal care services and client satisfaction are interrelated concepts. Measuring quality of care conceptualized in such a broad manner represents a true challenge Studies have revealed positive correlations between patient satisfaction and health care utilization. The present study aimed to determine the level of satisfaction for pregnant women in Erbil society for provision of services and health care utilization. Cross sectional study was carried out on 300 pregnant women attending [MCH] maternal and child health unit of three primary health care center [PHC] in Erbil city [nazdar bamerni, mala-afandi, azadi] from 1st of March 2008 to the 5th of September 2008. The variables included were socio-economic state, age, occupation, address, educational state, religion, satisfaction with overall care provider, drug provision, tetanus vaccine, waiting time, and health education regarding family planning and breast feeding programs. About two third of the sample at age group 21-30 year, majority of women 76% was housewives, 43.3% with primary school education, most of them 77.7% from moderate socioeconomic status,89.7% satisfied with care services available, 91.4% were satisfied with adequate medicine supply, 88.7% satisfied with tetanus vaccine supply, 84% of the sample satisfied with waiting time in less than one hour, while access of session in female health education talking about important family planning and birth spacing method were19.4%, and information of benefit breast feeding 42.3%.The study revealed that majority of women satisfy with health care services but Erbil need to improve in the program of health education regarding family Planning and benefits of breast feeding


Subject(s)
Humans , Female , Maternal-Child Health Centers , Pregnancy , Prenatal Care , Delivery of Health Care , Cross-Sectional Studies , Health Education , Family Planning Services , Breast Feeding
17.
Medical Forum Monthly. 2010; 21 (11): 2-4
in English | IMEMR | ID: emr-108626

ABSTRACT

This is the largest report to investigate the importance of platelet screening tests in patients with hepatic cirrhosis. One hundred eighty seven patients were examined in this study. On an appropriate clinical historic back ground, biochemical results and biopsy - proven cirrhotic patients were investigated. An abnormal bleeding time was found in 78 patients. There were significant differences between the group of patients with an abnormal bleeding time and the group with a normal bleeding time with respect to platelet count, prothrombin time and serum bilirubin concentrations [all p < 0.05]. We recommend to measure the bleeding time in patients with raised bilirubin concentrations or poor hepatic function, even if platelet counts and prothrombin time are with in [safe limits], before making a decision about potentially dangerous therapeutic measures, such as surgery


Subject(s)
Humans , Platelet Count , Prothrombin Time , Bilirubin/blood , Bleeding Time
18.
Medical Forum Monthly. 2010; 21 (11): 24-27
in English | IMEMR | ID: emr-108631

ABSTRACT

To investigate glucose tolerance and insulin response in myocardial infarction patients in type-2 diabetic population, normoglycemic FDRs or type-2 DM patients and MI with out DM and having no history of type-2 DM in family. Sixty five MI patients and twenty two healthy controls were selected for study. Subjects were divided in to four groups. The study was conducted for the period of 9 months in cardiology ward of various hospitals. Fasting plasma glucose levels in diabetic patients were abnormally higher as compared to other groups. Mean insulin level of FDRs and diabetic MI patients were significantly higher than controls and non diabetics. When viewed with higher fasting glucose level in groups, indicates considerable resistance. Higher insulin levels of FDRs may indicate start of insulin resistance at normoglycemic control. Finally we conclude that insulin resistance appears to be risk factors in diabetics and FDRs MI groups, while in non diabetics, non FDRs, MI patients these risk factors does not seem to play major role


Subject(s)
Humans , Male , Female , Myocardial Infarction , Glucose Tolerance Test , Insulin/blood , Insulin Resistance
19.
Medical Forum Monthly. 2010; 21 (4): 15-18
in English | IMEMR | ID: emr-97693

ABSTRACT

To find out frequency of dermatophytosis in Karachi and correlation between clinical types and strain isolated. This prospective study was conducted in the Department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi from September 2000 to August, 2001.Three hundreds seventy-three patients having skin, hair and nail infection [clinically suspected cases of dermatophytosis] were examined. The skin scraping, hair plucking and nail clipping were taken and subjected to direct microscopy and culture on mycobiotic agar [Difco] for isolation of dermatophytes. Various special media were used for species identification. Dermatophytosis was predominantly found among adults 246 [66.8%] population. Most common clinical pattern was of tinea corporis [26.9], followed by tinea cruris [25.8],tinea unguium [19.3], tinea capitis [17.4], tinea pedis [7.9], tinea faciei [4.6] tinea manuum [2.2] and tinea barbae [0.8] respectively. Tinea cruris was significantly found more in males 83 [36.9%] than females 12 [8.4%] [P<0.001]. Species of dermatophytes were recovered from 184 cases, out of which 95 [51.6%] strains of Trichophyton rubrum, 43 [23.4%] strains of Trichophyton violaceum, 25 [13.7%] strains of Epidermophyton floccosum,15 [8.2%] strains of Trichophyton mentagrophytes and 06 [3.2%] strains of Trichophyton tonsurans respectively. Trichophyton rubrum was found to be commonest etiological agent in different clinical types. Dermatophytosis is found to be more common in adult population. Tinea cruris being more common in miles while tinea corporis and tinea unguium relatively common in females Trichophyton rubrum was found to be commonest etiological agent in different clinical types


Subject(s)
Humans , Male , Female , Adolescent , Adult , Dermatomycoses/microbiology , Prospective Studies , Dermatomycoses/epidemiology , Age Distribution , Sex Distribution
20.
Medical Forum Monthly. 2009; 20 (9): 48-51
in English | IMEMR | ID: emr-111286

ABSTRACT

To find out the frequency of dermatophytosis in Karachi in relation to variation in climatic conditions. This study was conducted in the Department of Microbiology, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi from September 2000 to August, 2001. Three hundreds seventy-three patients having skin, hair and nail infection [clinically suspected cases of dermatophytosis] were examined. The skin scraping, hair plucking and nail clipping were taken and subjected to direct microscopy and culture on mycobiotic agar [Difco] for isolation of dermatophytes. The results indicated a strong correlation between dermatophytosis and certain climatic conditions. With the rise in temperature and humidity a corresponding rise in the frequency of dermatophytosis was recovered. The frequency increases in summer and decreases in winter. Most cases were recorded during May to August and then a gradual decline was observed. High temperature and humidity are the factors responsible for increase-frequency of dermatophytosis. There is strong correlation of dermatophytosis with variation in climatic conditions, the infection more frequent in hot and humid weather


Subject(s)
Humans , Climate Change , Arthrodermataceae
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